Impact

Our investments have contributed to the development of numerous marketed products. We take pride in having contributed to their success.

Therapeutics

Extended release, oral ion-channel blocker to improve walking in Multiple Sclerosis patients.

Opioid agonist for the management of severe pain.

Topical testosterone for treating males with low or no testosterone.

Antibiotic to treat acute bacterial skin and skin structure infections (ABSSSI) in both intravenous (IV) and oral formulation.

Indicated for use with other heart medicines to treat heart failure in African American patients.

First bi-specific antibody for the treatment of acute lymphoblastic leukemia.

Generic LOVENOX®, low molecular-weight heparin to prevent and treat deep vein thrombosis.

Injectable bradykinin receptor antagonist for the treatment of acute hereditary angioedema.

The first oncolytic viral therapy for the local treatment of recurrent melanoma.

Subcutaneously administered GLP-1 agonist for type 2 diabetes.

The first once-daily antibiotic to treat CABP and ABSSSI that is available in both an intravenous (IV) and oral formulation.

Immediate-release, oral oxycodone HCl for acute and chronic pain.

Roxadustat is a first-in-class, oral drug for the treatment of anemia in chronic kidney disease patients on dialysis.

An oral opioid receptor ligand for treating alcohol dependence.

Sarecycline is a tetracycline-derived antibiotic for the treatment of moderate to severe acne vulgaris.

Novel nasal spray formulation of an NSAID for pain management.

Inhalable bronchodilator treatment for chronic obstructive pulmonary disease.

Extended-release tablets for treating chronic hepatitis C virus infection.

Used with levodopa to control motor fluctuations in Parkinson’s disease patients.

Indicated for treating chorea associated with Huntington’s disease.

First IV and oral antibiotic with a novel mechanism of action approved by the FDA in nearly two decades. Treats community-acquired bacterial pneumonia (CABP) in adults.

ZEMDRI™ (plazomicin)—an antibiotic indicated for the treatment of complicated urinary tract infections (cUTI), including pyelonephritis.

Instruments and Research Tools

Andrew, the liquid handling robot designed to enhance the reproducibility and efficiency of the pipetting process.

Andrew+, the second generation liquid handling robot, can perform a wide range of complex experimental steps.

One-Lab, cloud-based intelligent laboratory software to design and execute liquid handling protocols.

High-throughput system for PCR-based genotyping, gene expression, and microRNA analysis.

Pipette+, the first connected smart pipetting system for maximum experiment repeatability with the minimum of effort.

Sophion Qube, a high throughput system for ion channel screening.

Medical Devices

CryoConsole: Cardiac Cryoablation System for treating paroxysmal atrial fibrillation.

Hydrosurgery system for minimally invasive spine surgery.

Diagnostics and Other Products

Weed control solution containing genetically modified soybean plants and tailor made herbicides.

The first blood test for colorectal cancer screening.

Assay for detection of mSHOX2 in patients suspected of having lung cancer.

MagnetOs Putty is indicated for use as an osteoconductive and osteoinductive bone void filler in the skeletal system.

Breast cancer recurrence assay.

Neuroseal is a synthetic tissue sealant candidate for the prevention of CSF leakage following cranial or spinal surgery.

Nevisense is the world’s first objective diagnostic support tool for non-visual detection of malignant melanoma.

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